SOLNAC is a corporate body composed of twelve members appointed by the presidency.  Members are drawn from the government, civil society organisations (CSOs), PLWHAs, religious and community leaders selected for their outstanding expertise and their commitment to the HIV & AIDS struggle.

The Commission is chaired by the President of the Republic of Somaliland and serviced by a full-time Secretariat headed by a full-time Executive Secretary, who is also secretary to the Commission. The Secretariat includes the following departments and units:

         Capacity Building department

         Prevention, Care and Treatment department

         Communication and Social Mobilization department

         Administration and Finance department

         Monitoring & Evaluation Unit

         Gender & HIV unit